From feeling exhausted all the time I have progressed to the point that I see Collette every few months and am able to live my life to the full! Thank you so much!

The Perrin Technique™ is a specialist technique designed for the diagnosis and treatment of Myalgic Encephalopathy (ME) and Chronic Fatigue Syndrome (CFS).

The Perrin Technique technique has also seen some benefits to patients suffering with Fibromyalgia and similar Systemic Exertion Intolerance Diseases as they are acknowledged as being on the same 'spectrum'.
The Perrin Technique is based on the research carried out by Dr Raymond Perrin, based at The Perrin Clinic, Prestwich.

The Perrin Technique determines ME is a result of different stress factors on the body cause an overstrain of the sympathetic nervous system leading to lymphatic breakdown and toxic build-up.

Dr Perrin has discovered definite physical signs common to all ME and CFS sufferers and he has provided a small article on the physical signs of ME/CFS - which you can read here.

Our Principal Osteopath Collette Nelstrop has been qualified and practicing in The Perrin Technique for over 10 years at receives a number of patients across Cheshire, Staffordshire and Manchester for the treatment of ME and CFS.

Collette's expertise were recognised in 2013 when she was awarded "Excellence in the Practice in The Perrin Technique".

Collette continues to practice alongside Dr Perrin at The Perrin Clinic in Prestwich where she is party to the latest research and developments.



Myalgic Encephalopathy is an illness estimated to affect some 250,000 people across the UK. There are a number of different names for the condition, such as:

Myalgic Encephalopathy or “ME” 

Chronic Fatigue Syndrome or “CFS”

Post-Viral Fatigue Syndrome or “PVFS”

Chronic Fatigue Immune Dysfunction Syndrome or “CFIDS”

ME is a wide spectrum in that all types of people from different backgrounds and ages are affected.

Some may experience minimal affects whilst others will have their lives drastically change, disrupting schooling, employment, social and their family lives.
People typically suffer from severe and debilitating fatigue, painful muscles and joints. Many people will also experience disordered sleep, gastric disturbances, poor memory and concentration.

Whilst the reasons for the onset of ME are not currently known it is thought that triggers may be linked to viral infections, an operation, accident and stress.

However, the symptoms may only become apparent after a prolonged period of time.



The causes are not yet fully understood but through Dr Perrin’s research he discovered that the probable cause for ME and CFS is nervous system overload due to stresses on the body causing build-up of toxins in the fluid around the brain and the spinal cord.

These stresses can be emotional, physical trauma, viral, environmental and infective, and ususally a combination of these.

The result of this is a break down of the lymphatic system and therefore the build-up of poisons.

In ME and CFS sufferer the normal drainage points have become congested causing this back up of toxins which irritate the brain, spinal cord and tissues causing the wide range of symptoms suffered.



Dr Perrin devised and developed The Perrin Technique following a chance encounter with a patient suffering with ME who came to him with lower back pain and found his ME, in his eyes, 'cured' following Dr Perrin's osteopathic treatment.

After years of research and trials Dr Perrin had devised and developed The Perrin Technique to diagnose and treat ME and CFS.

The technique gives an immediate diagnosis after the patient's first physical examination, rather than the diagnosis of ME and/or CFS being a process of elimination, as seen in mainstream medicine.

The diagnostic element of The Perrin Technique is forming the basis of a NHS research project at Wrightington Hospital in Wigan.

The research project is solely focused on the diagnosis of ME and CFS and commenced in July 2015 for a full 12 months before results are ready for publishing in the summer of 2016.



The Perrin Technique™ is an osteopathic approach designed to manually stimulate the fluid motion around the brain and spinal cord, encouraging drainage of the lymphatic system.

Manipulation of the spine and tissues further aid drainage of these toxins out of the cerebrospinal fluid.
Through gentle manipulation of soft tissues in the head, neck, back and chest The Perrin Technique directs all the toxins out of the lymphatic system and into the blood, where they are eventually detoxified in the liver.
Eventually with no poisons affecting the brain, the sympathetic nervous system begins to function correctly.  
Providing the patients do not overstrain themselves their symptoms should gradually improve and in time some patients become totally symptom free.